Friday, September 27, 2013

Dianabol - The First Ever Anabolic Steroid

Dianabol was the first ever anabolic steroid that was a potent mixture of both anabolic and androgenic properties, and that's what made it one of the strongest and the most popular drugs of its time. Dianabol certainly is considered as one of the groundbreaking anabolic steroids. It was first produced by John Ziegler with collaboration with the Ciba Laboratories in 1956.

Dianabol was introduced in the United States in 1958. The anabolic steroid became extremely popular in the States. It virtually became the favorite supplement of bodybuilders and weightlifters. The drug is said to be the favorite of Arnold Schwarzenegger.

Dianabol is known for its ultimate potential of improving muscle size with least fluid retention. It also helps in suppressing or choking up signals which keep your muscles intact. It is also known as D-Bol or methandrostenolone in the pharmaceutical field. It is referred to as a muscle growth hormone. It has a 17a methyl group formula which helps it to pass through the liver and slow down the rate of conversion to estrogen. The drug has the capability of water retention which further helps in gaining great muscle mass and strength. It also promotes protein synthesis, enhances glucogenolysis and stimulates strength in a very fast-acting way.

However, the drug has some serious kind of side effects, which really compelled the US FDA to ban it. Some of the side effects generally linked with Dianabol include - acne, hair loss, headache, masculinising effects in women, increased blood pressure, and strain on the liver.

Dianabol was scaling the peaks of popularity when the FDA banned it in the year 1990. People however continued to use this drug even after it was banned. The drug is not really prescribed for women, but for men its dose is 15-50mg/daily orally or 50-150mg/week by injection. Nowadays, the drug is being produced by the Mexican pharmaceutical companies and is sold under the name Reforvit - b. 

Tuesday, September 24, 2013

Testosterone Propionate

Testosterone Propionate is an esterified form of the base steroid testosterone, much like enanthate, cypionate and sustanon 250. It's a superlipophillic, oil-based injectable that slows the release of the steroid into the blood stream. But compared to enanthate and cypionate, testosterone propionate is a very short ester and is still released quite fast. As such more frequent injections are needed. Levels will peak after 24-36 hours and begin tapering from there on out, making the longest possible time-span between injections, at least or proper results, about 3 days. Most athletes will opt to inject 50-100 mg every day to every other day.

It's not the most user-friendly steroid of them all. Frequent injections can be painful to begin with, to a point where users will begin scouting for different locations to stick the needle, in order to not aggravate the same spots all the time. To make matters worse, its not that pleasant to inject either. The injection-site can become irritated and swell, and sometimes give incredible itches or soreness when touched. All these factors combined, you can see that this is the best form of testosterone to start off on for most beginners. And still. As discussed with enanthate and cypionate, a long-acting ester requires some skill with ancillary drugs and familiarity with post-cycle protocol since simple discontinuation will not put a halt to all problems. In that aspect, for those who do not master ancillaries and post-cycle therapy, propionate is perhaps a better product to start off with. Levels of androgens and estrogens will drop within 2-4 days of discontinuation, effectively halting or reducing any occurring side-effects. Nonetheless, this is a testosterone with a high risk of side-effects (the characteristics of testosterone do not change despite the ester, which is just a carrier) so the use of Nolvadex/proviron/Arimidex and so forth is highly advised if you plan to see a cycle through.

What is of note with propionate, is that users have successfully incorporated it into cutting cycles as well. Especially people who tend to lose a lot of mass normally during extreme diet phases find this useful. By injecting every two or three days and using only 50-75 mg each time, no notable water builds up (or at least none that can't be fixed with proviron, arimidex or winstrol) and no fat is deposited, thus allowing a user to stay relatively lean. So this type of testosterone can be used to keep gaining or retaining mass until 2-3 weeks out of contest time with relatively little difficulty. Although most will choose to add Proviron (50-100 mg/day) out of precaution. Its best use is of course still in bulking phases to pack on mass. Testosterone is not the king of the hill of all mass-builders for nothing.

On the American black market propionate is not an extremely available item, its most popular in Europe, where its use is more wide-spread than that of the long-acting esters. Its nonetheless a desired item almost anywhere in the world because it's a very controllable form of what is no doubt the most powerful steroid ever. The cost is quite high too, easily running 2 to 3 times more for a weekly dose than enanthate, cypionate or sustanon 250.

Stacking and Use:

As a short-lived oil based injectable, most will want to opt for doses of 50-100 mg every day to every other day. Those of a lighter stature seeking to use it for cutting purposes may want to make that every 2nd or 3rd day, or add proviron as a precaution instead, 50-100 mg/day sufficing in most cases. The site of injection is best rotated each time, or problem can occur. The compound is irritative and the damage to the skin and underlying tissue can cause some cosmetic problems if it becomes repetitive. Subcutaneously , balls of fat or tissue can build up. In most cases these need to surgically removed. So rotating is wise.

For bulking purposes one is best to stack testosterone with a base compound such as Deca-durabolin (nandrolone) or Equipoise (boldenone), and can addition Dianabol (methandrostenolone) or Anadrol (oxymetholone) for 5-6 weeks, at the beginning, to kickstart the gains a bit. Most will choose for a more user-friendly, longer-acting testosterone for bulking purposes however. For cutting, the best and primary addition is that of Proviron, which will reduce if not stop estrogen build-up, increase muscle hardness and strength and allow for a higher free testosterone level. But naturally other compounds lend themselves quite well too. Base compounds such as Equipoise or Primobolan (methenolone) making a good match for longer stacks, and towards contest time steroids such as Anavar (oxandrolone), finaplix (Trenbolone) or Winstrol (Stanazolol) make the best matches, as they too will help increase muscle hardness and decrease body-fat, while maintaining lean muscle mass. With testosterone, most any combination is possible. Because testosterone is always the stronger compound in a stack.

In terms of ancillaries, the use of anti-estrogens is advised. For cutting puposes one will want to run Proviron alongside the testosterone for the length of the stack, which will rarely make the use of other anti-estrogens a necessity. If no Proviron or arimidex is used, you may want to keep some Nolvadex handy. Should problems arise starting on 20-40 mg of Nolvadex until a while after problems subside should be sufficient for all intents and purposes. Testosterone, being a heavily aromatizing compound, is also quite suppressive of natural testosterone (most so, safe for nandrolone) so a post-cycle therapy with Nolva/Clomid and HCG is necessary. Usually one will start HCG the last week or two weeks of a stack and run it about 4 weeks. HCG shots of 1500-3000 IU given every 5th or 6th day. That means during the end of a cycle, one shot of HCG is given per two shots of testosterone. A user should also opt to wait on using clomid or Nolvadex until the androgen is cleared. For longer esters that was 1.5 to 2 weeks, obviously that time-frame should be reduced to 1 week or even half a week for propionate. One will then start on either 40-50 mg of Nolvadex or 150 mg of Clomid per day for a period of two weeks, and then follow it up with 20-25 mg of Nolvadex or 100 mg of Clomid per day for another two weeks. Post-cycle therapy will facilitate the return of natural testosterone and make it more likely for the user to retain most of the mass he gained while on the cycle.

Tuesday, September 17, 2013

Common Steroid Pills: Types & Effects Of Use

Search Engines, what a luxury they are to Buy steroids! For they are a real comfort to those bootlegging myriad of extrajudicial poppin' pills, which frequently include Steroids! These pills are often based on various male sex hormones that lead to the development of secondary male sexual characteristics, for instance, testosterone. They are medically termed as Androgens & Anabolic Steroids, although on the street, they are better known as - juices, toners or candy!

As their name suggests, these steroids have both anabolic and androgenic effects. Through a combination of these effects, anabolic steroids stimulate muscle formation leading to increased muscle mass and strength. Some of the most commonly used steroids, both medicinally as well as otherwise, include, but are not limited to:

1. Prednisone: It is a dehydrogenated analogue of cortisol which is used as an anti-inflammatory drug in the treatment of arthritis and as an immunosuppressant. Thus, it is used in a wide range of autoimmune diseases such as severe asthma, allergies, rheumatoid arthritis, and to prevent and treat rejection in organ transplantation.

2. Nandrolone: It is an androgen (trade names: Durabolin or Kabolin) that is used to treat testosterone deficiency or breast cancer or osteoporosis. The positive effects of the drug include muscle growth, appetite stimulation, increased red blood cell production and increased bone density.

3. Equipoise: It is an anabolic steroid developed for veterinary use, mostly for treatment of horses. It has low androgenic activity and is often used by bodybuilders for adding strength and size because it increases the appetite. It is well known for increasing vasculature.

4. Dehydroepiandrosterone (DHEA): It is the most abundant androgen secreted by the adrenal glands. Some reports are indicative of its role in the aging process as circulating levels of DHEA peak at age 25 and then steadily decline with age. DHEA deficiencies in older individuals have been associated with a number of medical conditions including breast cancer and cardiovascular disorders and thus it has been suspected for potent anti-ageing roles.

5. Anavar: It was designed as an extremely mild anabolic and has been extensively used for treatment of alcoholic hepatitis, Turner's syndrome, and weight loss caused by HIV. This steroid works well for the promotion of strength and duality muscle mass gains; although it's mild nature makes it less than ideal for bulking purposes.

6. Winstrol: The anabolic properties of Winstrol are mild in comparison to many other steroids and thus, it is stacked with other testosterone-based anabolic steroids. It increases strength without excess weight-gain, promotes vasculature and is thus pretty famous amongst body builders.

7. Steranobol: Chemically, steranobol has a chloro- group added at the 4-position of testosterone. It is an artificial, synthetic androgenic steroid with anabolic effects similar to testosterone. It is frequently used illegally to improve physical performance in sports and athletics and thus, is prohibited by many sports authorities, including the International Olympic Committee.

8. Testosterone: Testosterone itself has been taken externally to enhance muscle development, strength, and endurance. They do so directly by increasing the protein synthesis in muscle cells. As a result, muscle fibers become larger and repair faster than they do normally.

9. Tetrahydrogestrinone: It is a structurally modified anabolic androgenic steroid that is prohibited in sports. It was developed to flim-flam the sports authorities via manipulation of another prohibited substance to illicitly enhance sports performance.

10. Clenbuterol: It is a widely used bronchodilator in many parts of the world. In animal studies, clenbuterol has shown to exhibit anabolic activity which is a highly attractive attribute for pixilated sportspersons. It is known to directly stimulate the adipose tissue and accelerate the breakdown of triglycerides to form free fatty acids. It is used as a pre-contest drug.

Friday, September 6, 2013

Anavar and Sustained Weight Loss

One of the steroids that fit women well, Anavar (oxandrolone) is a drug that is mild on all fronts: mildly anabolic, mildly androgenic, mildly affects the hypothalamic-testicular-pituitary-axis (HTPA), and most important, mildly toxic to the liver compared to other steroids. These properties make this a popular, albeit expensive, anabolic drug, especially for top-level female athletes.

Originally made by Searle in the US but was discontinued after too much negative publicity, this drug is manufactured by companies like British Dragon Thailand and La Pharma Anavar Italy. It is currently marketed under trade names Oxandrin and Oxanabol. Anavar (slang name: var) is a class 1 steroid as it binds well with androgen-receptors (under the arbitrary classification system that is based on AR interaction).

While it is a strong AR agonist, the lack of non-receptor mediated mechanisms such as protein synthesis makes oxandrolone a weak anabolic steroid. Thus, it requires rather large doses for it to be effective; combating muscle-wasting in AIDS, for example, requires administration of Anavar in 20-80mgs doses. It is no wonder that male bodybuilders don't favor this drug well, as it is quite expensive and doesn't give much in return.

Another characteristic of Anavar, which is considered good especially by women, is its poor androgenic properties. It doesn't raise estrogen levels so the common side effects associated with AAS gynecomastia and water retention- are unheard of when using this drug. However, it may increase low-density lipoprotein (bad cholesterol) and reduce high-density lipoprotein (good cholesterol) which can cause blood pressure problems. For women, masculinizing effects such as body/facial hair growth and deepening of voice are minute and are therefore not a concern when using Anavar.

Unlike other 17-alkylated steroids, liver toxicity is considered insignificant when using Anavar, unless administered in very large doses and used for prolonged periods. It doesn't pose as much hepatotoxic effects as Dianabol (methandrostenolone), another testosterone derivative that is altered at the 17th carbon atom (this alteration is usually done for orally-administered drugs to be able to survive the pass through the liver).

Anavar also shows minimal effect on the HTPA, particularly on low doses. Oxandrolone does not aromatize to estrogen, and suppression of the serum testosterone, Sex Hormone Binding Globulin (SHBG) and Luteinizing Hormone (LH) is slight. Of course, like other anabolic steroids, the effect worsens as the dose increases..

One characteristic that sets Anavar apart is its unusual fat-burning ability. One study shows that the drug reduced abdominal and visceral fat on subjects with low/normal natural testosterone [1]. In another research, appendicular, total, and trunk lipids were lowered with 20mgs/day of Anavar, without any exercise [2]. In addition to its fat-burning properties, the drug also allows permanent muscle gains. The muscle you get when you use Anavar may not be much, but you got to keep it after you stop taking the drug, as shown by a study wherein the subjects maintained their weight six months after stopping Anavar medication.
With this mixture of interesting and exciting effects that impact health enthusiasts, it is no wonder that Anavar gained many adherents. This is especially true for women, as it seems that the drug suits them well in all aspects particularly with the relatively low dosage indicated for them. The fat-burning and weight-sustaining effects of Anavar are additional benefits that make the drug more attractive.